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 Hope for metastatic skin cancer?
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the_ignored
SFN Addict

2557 Posts

Posted - 04/08/2010 :  12:49:27  Show Profile Send the_ignored a Private Message  Reply with Quote
They're only in the Phase III trials now, but so far, it looks hopeful.

Abbie has more information and links.

A modified Herpes Simplex Virus-1. Regular ol HSV-1 that we are basically all infected with, causes cold-sores in some people? Yeah, scientists gutted out some bits of it (keep it from going into neurons, make it need something cancers make lots of), added immune-stimulating bits (a chemical messenger that REALLY pisses off macrophages).

This modified virus was injected directly into melanoma lesions every two weeks for up to 48 weeks (24 doses). Now, remember these patients were metastatic-- yes, they had 'skin cancer', but that cancer had spread, to the liver/lungs/anywhere.

Even though the virus was injected into the 'skin cancer', the liver lesions, the lung lesions-- they were all killed too. Scientists aspirated where the lesions used to be, and all there was was necrotic tissue (dead cancer).

>From: enuffenuff@fastmail.fm
(excerpt follows):
> I'm looking to teach these two bastards a lesson they'll never forget.
> Personal visit by mates of mine. No violence, just a wee little chat.
>
> **** has also committed more crimes than you can count with his
> incitement of hatred against a religion. That law came in about 2007
> much to ****'s ignorance. That is fact and his writing will become well
> know as well as him becoming a publicly known icon of hatred.
>
> Good luck with that fuckwit. And Reynold, fucking run, and don't stop.
> Disappear would be best as it was you who dared to attack me on my
> illness knowing nothing of the cause. You disgust me and you are top of
> the list boy. Again, no violence. Just regular reminders of who's there
> and visits to see you are behaving. Nothing scary in reality. But I'd
> still disappear if I was you.

What brought that on? this. Original posting here.

Another example of this guy's lunacy here.

Edited by - the_ignored on 04/08/2010 12:53:09

Starman
SFN Regular

Sweden
1613 Posts

Posted - 04/08/2010 :  22:50:31   [Permalink]  Show Profile Send Starman a Private Message  Reply with Quote
Nice!

I've heard about plans for anti-cancer viruses before and its nice to see that they have reached trial stage.

My parents lost a good friend to metastatic skin cancer. She was able to hang on until she became a grand mother but just barely. I'll guess examples are abundant.

"Any religion that makes a form of torture into an icon that they worship seems to me a pretty sick sort of religion quite honestly"
-- Terry Jones
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HalfMooner
Dingaling

Philippines
15831 Posts

Posted - 04/08/2010 :  23:34:17   [Permalink]  Show Profile Send HalfMooner a Private Message  Reply with Quote
That's wonderful stuff! I bet the treatment is gentle to the patient, compared to other aggressive treatments of (almost hopeless) metastatic melanoma.

Biology is just physics that has begun to smell bad.” —HalfMooner
Here's a link to Moonscape News, and one to its Archive.
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