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 ccdi9 revisited
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Plyss
Skeptic Friend

Netherlands
231 Posts

Posted - 03/18/2005 :  08:06:50   [Permalink]  Show Profile Send Plyss a Private Message
quote:
Originally posted by Dave W.


Turns out that Hannah, when asked about "micro-proteinoids," claims to have discovered them. She says the whole "ccdi9" thing is her hypothesis, and her PhD work, and implies that's why none of this stuff can be found on the Web.

To anyone with an inside knowledge of how doctorate-level work is done: does this make any sense at all? Do doctoral candidates often invent at least two new terms for the things they're working on? Or is Hannah making herself out to be the next freakin' Einstein (of biochemistry)?



The earliest reference i could find about proteinoids date back to the early sixties. These proteinoids are non-biological strings of amino-acids ranging between 30 and a hundred amino acids. Presumbably a "micro-proteinoid" is a string of amino acids that is smaller than this.

The "codes" in her post could refer to combinations of amino acids, but that doesn't really make sense considering all the biologically relevant ones are named and every conceivable amino acid also has a systematic IUPAC name.

How any of this provides a challenge for evolution or even abiogenesis is unclear to me.

In doctoral research it is not unheard of to come up with your own terms for novel things you run into. Whether or not the term sticks around and makes it into the final publication depends a bit on the professor you work under.
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Dave W.
Info Junkie

USA
26014 Posts

Posted - 03/18/2005 :  08:35:31   [Permalink]  Show Profile  Visit Dave W.'s Homepage Send Dave W. a Private Message
quote:
Originally posted by Plyss

The earliest reference i could find about proteinoids date back to the early sixties. These proteinoids are non-biological strings of amino-acids ranging between 30 and a hundred amino acids. Presumbably a "micro-proteinoid" is a string of amino acids that is smaller than this.
Also known as polypeptides, unless the "non-biological" part makes the "peptide" label inappropriate.
quote:
The "codes" in her post could refer to combinations of amino acids, but that doesn't really make sense considering all the biologically relevant ones are named and every conceivable amino acid also has a systematic IUPAC name.
Yeah, so it also makes no sense that a friend of hers is inventing names for them.
quote:
How any of this provides a challenge for evolution or even abiogenesis is unclear to me.
It doesn't, according to Hannah. It just presents a challenge to gradualistic evolution. I think she's actually an IDist.

- Dave W. (Private Msg, EMail)
Evidently, I rock!
Why not question something for a change?
Visit Dave's Psoriasis Info, too.
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Plyss
Skeptic Friend

Netherlands
231 Posts

Posted - 03/18/2005 :  10:01:07   [Permalink]  Show Profile Send Plyss a Private Message
quote:
Originally posted by Dave W.
Also known as polypeptides, unless the "non-biological" part makes the "peptide" label inappropriate.



Yeah, i should have phrased that better. Typically non-biological peptides are refered to as artifical peptides or synthetic peptides.
The term "proteinoids" seems to refer solely to these polypeptide-chains that are made via the thermal method described by Sydney Fox and coworkers.

Incidentally, the method they used looks pretty easy and i have all the required material standing ready in the lab. Perhaps i'll give it a try tomorrow, it looks pretty cool :)
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Dave W.
Info Junkie

USA
26014 Posts

Posted - 03/18/2005 :  10:03:07   [Permalink]  Show Profile  Visit Dave W.'s Homepage Send Dave W. a Private Message
Make some tiny ones. Then you can compete with Hannah on "micro-proteinoid" work.

- Dave W. (Private Msg, EMail)
Evidently, I rock!
Why not question something for a change?
Visit Dave's Psoriasis Info, too.
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Plyss
Skeptic Friend

Netherlands
231 Posts

Posted - 03/19/2005 :  04:38:34   [Permalink]  Show Profile Send Plyss a Private Message
quote:
Originally posted by Dave W.

Make some tiny ones. Then you can compete with Hannah on "micro-proteinoid" work.



I'm running Fox' protocol right now. The mixture gives of a nice spicy scent and it had the colour that Fox reported it should have. I fear the 3h incubation time may be to long for my equipment though as it's starting to turn black.
If i get around to it i'll run the mixture on Laemli's gel-electrophoresis system this evening, i'm kind of curious if there's anything protein-like in it.
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